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Genetically altered mosquitoes thwart dengue spreaders

点击量:   时间:2019-03-07 14:05:01

GENETICALLY modified male Aedes aegypti mosquitoes could provide a potent new weapon against dengue fever, a disease which infects 50 million people annually and kills 25,000. In a six-month trial on the Caribbean island of Grand Cayman, 3.3 million of the mutant males were released into the wild. By the end of the trial the population of dengue-carrying A. aegypti females appeared to have plummeted. Oxitec, a company in Oxford, UK, bred males with an altered gene called tTA. This overcommits the gene transcription machinery of larvae and pupae,