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Opioid crisis: powerful but non-addictive drug could replace morphine

点击量:   时间:2019-03-04 06:06:01

A NEW opioid drug has been shown to stop monkeys feeling pain, without any apparent addictive or harmful side effects. Opioids such as morphine stop pain, but can also be addictive. In the US alone, more than 46 people die daily from overdoses of prescription opioids. Mei-Chuan Ko at Wake Forest University in North Carolina and his colleagues have found that a drug called AT-121 blocks pain by activating two types of opioid receptor in the brain. One is the mu opioid receptor, the pain-relieving receptor targeted by many opioids. The other is the nociceptin opioid receptor,